ChloroquineV1, Main, Exploration, bibRecord, 002433

Chronic interstitial lung disease in children.

Identifieur interne : 002433 ( Main/Exploration ); précédent : 002432; suivant : 002434

Chronic interstitial lung disease in children.

Auteurs : A. Barbato [Italie] ; C. Panizzolo

Source :

Paediatric respiratory reviews [ 1526-0542 ] ; 2000.

RBID : pubmed:12531111

Descripteurs français

KwdFr :
- Enfant, Humains, Maladie chronique, Pneumopathies interstitielles (), Pneumopathies interstitielles (diagnostic), Pneumopathies interstitielles (étiologie), Pronostic.
MESH :
- diagnostic : Pneumopathies interstitielles.
- étiologie : Pneumopathies interstitielles.
- Enfant, Humains, Maladie chronique, Pneumopathies interstitielles, Pronostic.

English descriptors

KwdEn :
- Child, Chronic Disease, Humans, Lung Diseases, Interstitial (classification), Lung Diseases, Interstitial (diagnosis), Lung Diseases, Interstitial (etiology), Lung Diseases, Interstitial (therapy), Prognosis.
MESH :
- classification : Lung Diseases, Interstitial.
- diagnosis : Lung Diseases, Interstitial.
- etiology : Lung Diseases, Interstitial.
- therapy : Lung Diseases, Interstitial.
- Child, Chronic Disease, Humans, Prognosis.

Abstract

Chronic interstitial lung disease (ILD) is rare in children, but is clinically relevant because of its high morbidity and mortality rates. Several aetiological agents may have a role in this disease and various aetiopathogenic forms have been described, although they share a characteristic evolution towards pulmonary fibrosis. The aetiology sometimes remains unknown, in which case we speak of idiopathic interstitial pneumonia (IIP). Diagnosis relies on non-invasive methods (clinical history, respiratory function tests, chest X-ray and high-resolution CT scan) and invasive techniques (bronchoalveolar lavage, transbronchial biopsy, video-assisted thoracoscopic biopsy and open lung biopsy); the latter are used when the former fail to identify an aetiological agent. The gold standard for the diagnosis is lung biopsy, however, which also enables the classification of the idiopathic forms, in particular (usual interstitial pneumonia, desquamative interstitial pneumonia, non-specific interstitial pneumonia, and so on). In ILD, the most common therapeutic approaches involve the use of oral steroids and hydroxychloroquine sulphate for its anti-inflammatory and antifibrotic effect. The prognosis is often poor.

PubMed: 12531111

Affiliations:

Italie

Le document en format XML

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<affiliation wicri:level="1"><nlm:affiliation>Department of Pediatrics, University of Padova, Italy. barbato@child.pedi.unipd.it</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Pediatrics, University of Padova</wicri:regionArea>
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<term>Lung Diseases, Interstitial (etiology)</term>
<term>Lung Diseases, Interstitial (therapy)</term>
<term>Prognosis</term>
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<term>Humains</term>
<term>Maladie chronique</term>
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<term>Pneumopathies interstitielles (diagnostic)</term>
<term>Pneumopathies interstitielles (étiologie)</term>
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<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Lung Diseases, Interstitial</term>
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<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Pneumopathies interstitielles</term>
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<term>Chronic Disease</term>
<term>Humans</term>
<term>Prognosis</term>
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<keywords scheme="MESH" xml:lang="fr"><term>Enfant</term>
<term>Humains</term>
<term>Maladie chronique</term>
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<front><div type="abstract" xml:lang="en">Chronic interstitial lung disease (ILD) is rare in children, but is clinically relevant because of its high morbidity and mortality rates. Several aetiological agents may have a role in this disease and various aetiopathogenic forms have been described, although they share a characteristic evolution towards pulmonary fibrosis. The aetiology sometimes remains unknown, in which case we speak of idiopathic interstitial pneumonia (IIP). Diagnosis relies on non-invasive methods (clinical history, respiratory function tests, chest X-ray and high-resolution CT scan) and invasive techniques (bronchoalveolar lavage, transbronchial biopsy, video-assisted thoracoscopic biopsy and open lung biopsy); the latter are used when the former fail to identify an aetiological agent. The gold standard for the diagnosis is lung biopsy, however, which also enables the classification of the idiopathic forms, in particular (usual interstitial pneumonia, desquamative interstitial pneumonia, non-specific interstitial pneumonia, and so on). In ILD, the most common therapeutic approaches involve the use of oral steroids and hydroxychloroquine sulphate for its anti-inflammatory and antifibrotic effect. The prognosis is often poor.</div>
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Serveur d'exploration Chloroquine

Chronic interstitial lung disease in children.

Chronic interstitial lung disease in children.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

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